Covid-19 Vitamin D

C

corsol

Guru
11. mar 2010
2.667
822
113
Uporabnik javr je napisal:
problem pri raznih proizvajalcih/prodajalcih D-vitamina je da v večini primerov ni preverjeno kaj sploh prodajajo. Edini preverjen bi naj bil od Krke in temu primerno ne-smešna je tudi cena
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Prehranski dodatki(vitamini itd..), so manj oz. Slabo regulirani, vendar glede na dostopne raziskave je vec ali manj v predpisanih okvirih(so sicer kar precejšnje tolerance....pri vitaminih se mi zdi da +-50%).
Da pa je od krke edini preverjen je pa vseeno mal huda...
 
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W

wildude

Fizikalc
24. jun 2008
1.556
28
48
Nedavno sem povprašal v lekarni. Farmacevtka je dejala, da je z vidika preventive (domača uporaba) varno dnevno vzeti do 4000 enot.
5 µg (200 IE)

D3 sem nabavil v DM. Za zdaj bom najprej ponucal A-Z Complete (Doppel herz), nato podobnega Abtei A-Z Komplett kombiniral z extra dodanim D3 (90 kapsul, NutriLAB, 800 IE ('dvojna' moč)). // Vzel bi tudi od kakega drugega proizvajalca, a je bil ta v času nakupa pri roki. Da ne bo kake opazke o reklamiranju ... :)
 
Nazadnje urejeno:
B81

B81

22. jul 2007
34.425
8.917
113
10000 ravno dobi kratkohlačnik na soncu v 20 minutah, je včasih veljalo :)
 
A

AndY1

Guru
Osebje foruma
18. sep 2007
22.038
4.049
113
www.medrxiv.org

COVID-19 mortality risk correlates inversely with vitamin D3 status, and a mortality rate close to zero could theoretically be achieved at 50 ng/ml 25(OH)D3: Results of a systematic review and meta-analysis

Background Much research shows that blood calcidiol (25(OH)D3) levels correlate strongly with SARS-CoV-2 infection severity. There is open discussion regarding whether low D3 is caused by the infection or if deficiency negatively affects immune defense. The aim of this study was to collect...
www.medrxiv.org www.medrxiv.org

COVID-19 mortality risk correlates inversely with vitamin D3 status, and a mortality rate close to zero could theoretically be achieved at 50 ng/ml 25(OH)D3: Results of a systematic review and meta-analysis​

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Results One population study and seven clinical studies were identified, which reported D3 blood levels pre-infection or on the day of hospital admission. They independently showed a negative Pearson correlation of D3 levels and mortality risk (r(17)=-.4154, p=.0770/r(13)=-.4886, p=.0646). For the combined data, median (IQR) D3 levels were 23.2 ng/ml (17.4 – 26.8), and a significant Pearson correlation was observed (r(32)=-.3989, p=.0194). Regression suggested a theoretical point of zero mortality at approximately 50 ng/ml D3.
Conclusions The two datasets provide strong evidence that low D3 is a predictor rather than a side effect of the infection. Despite ongoing vaccinations, we recommend raising serum 25(OH)D levels to above 50 ng/ml to prevent or mitigate new outbreaks due to escape mutations or decreasing antibody activity.
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C

corsol

Guru
11. mar 2010
2.667
822
113
...pobrskaj malo , za že večkrat objavljeno tabelo priporočenih doz,...al pa ker je spet aktualno ,če jo kdo objavi.
 
C

corsol

Guru
11. mar 2010
2.667
822
113
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D

darjan

Vulkanizer
13. sep 2007
51.262
6.521
113
Poleg je pametno K2 jemat, tako da raje potem vitd in k2 v enem. DM ima taksen sprej.
 
D

darjan

Vulkanizer
13. sep 2007
51.262
6.521
113
www.ncbi.nlm.nih.gov

The Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular Health: A Narrative Review

Vitamins D and K are both fat-soluble vitamins and play a central role in calcium metabolism. Vitamin D promotes the production of vitamin K-dependent proteins, which require vitamin K for carboxylation in order to function properly. The purpose of this ...
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

2x zjutraj spricnem in 2x zvecer, pod jezik in pustim, drugo ne kompliciram, edino nic drugega ne takoj za tem, po minuti pa ze komot :)
Taki rdeci sprej iz DM, mislim da cena 12€
 
J

johan_blond

Guru
19. jul 2007
2.762
1.493
113
Uporabnik AndY1 je napisal:
Zakaj pod jezik?
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Sublingual administration has certain advantages over oral administration. Being more direct, it is often faster, and it ensures that the substance will risk degradation only by salivary enzymes before entering the bloodstream, whereas orally administered drugs must survive passage through the hostile environment of the gastrointestinal tract, which risks degrading them, by either stomach acid or bile, or by enzymes such as monoamine oxidase (MAO). Furthermore, after absorption from the gastrointestinal tract, such drugs must pass to the liver, where they may be extensively altered; this is known as the first pass effect of drug metabolism. Due to the digestive activity of the stomach and intestines, the oral route is unsuitable for certain substances, such as salvinorin A.

Sublingual administration - Wikipedia

en.m.wikipedia.org en.m.wikipedia.org
 
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